According to the official Python.NET documention I'm supposed to install it using pip install pythonnet, this gives me an error however. I have upgraded the following packages trying to fix it:

• pip
• setuptools
• wheel

This however didn't fix it and it's throwing some errors.

Collecting pythonnet
  Using cached pythonnet-2.5.2.tar.gz (1.9 MB)
  Preparing metadata (setup.py) ... done
Requirement already satisfied: pycparser in c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages (from pythonnet) (2.21)
Building wheels for collected packages: pythonnet
  Building wheel for pythonnet (setup.py) ... error
  ERROR: Command errored out with exit status 1:
   command: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' bdist_wheel -d 'C:\Users\kiron\AppData\Local\Temp\pip-wheel-teu689ee'
       cwd: C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\
  Complete output (91 lines):
  running bdist_wheel
  running build
  running build_ext
  Checking for updates from https://www.nuget.org/api/v2/.
  Currently running NuGet.exe 4.1.0.
  Updating NuGet.exe to 6.0.0.
  Update successful.
  Cannot find the specified version of msbuild: '14'
  MSBuild auto-detection: using msbuild version '16.11.2.50704' from 'C:\Program Files (x86)\Microsoft Visual Studio\2019\Community\MSBuild\Current\bin'.
  Restoring NuGet package NUnit.ConsoleRunner.3.11.1.
  Restoring NuGet package NUnit.3.12.0.
  Adding package 'NUnit.3.12.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Adding package 'NUnit.ConsoleRunner.3.11.1' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Added package 'NUnit.ConsoleRunner.3.11.1' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Restoring NuGet package System.ValueTuple.4.5.0.
  Adding package 'System.ValueTuple.4.5.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Added package 'NUnit.3.12.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Restoring NuGet package UnmanagedExports.1.2.7.
  Adding package 'UnmanagedExports.1.2.7' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Added package 'System.ValueTuple.4.5.0' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'
  Added package 'UnmanagedExports.1.2.7' to folder 'C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\packages'

  NuGet Config files used:
      C:\Users\kiron\AppData\Roaming\NuGet\NuGet.Config
      C:\Program Files (x86)\NuGet\Config\Microsoft.VisualStudio.Offline.config

  Feeds used:
      C:\Users\kiron\.nuget\packages\
      https://api.nuget.org/v3/index.json
      https://packages.stride3d.net/nuget
      C:\Program Files (x86)\Microsoft SDKs\NuGetPackages\

  Installed:
      4 package(s) to packages.config projects
  Traceback (most recent call last):
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 396, in <module>
      sys.exit(main())
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 357, in main
      python_h = preprocess_python_headers()
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 238, in preprocess_python_headers
      for line in _check_output(cmd).splitlines():
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\tools\geninterop\geninterop.py", line 46, in _check_output
      output = subprocess.check_output(*args, **kwargs)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 420, in check_output
      return run(*popenargs, stdout=PIPE, timeout=timeout, check=True,
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 501, in run
      with Popen(*popenargs, **kwargs) as process:
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 966, in __init__
      self._execute_child(args, executable, preexec_fn, close_fds,
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 1435, in _execute_child
      hp, ht, pid, tid = _winapi.CreateProcess(executable, args,
  FileNotFoundError: [WinError 2] The system cannot find the file specified
  Traceback (most recent call last):
    File "<string>", line 1, in <module>
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 630, in <module>
      setup(
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\__init__.py", line 155, in setup
      return distutils.core.setup(**attrs)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\core.py", line 148, in setup
      return run_commands(dist)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\core.py", line 163, in run_commands
      dist.run_commands()
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 967, in run_commands
      self.run_command(cmd)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
      cmd_obj.run()
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 612, in run
      return bdist_wheel.bdist_wheel.run(self)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\wheel\bdist_wheel.py", line 299, in run
      self.run_command('build')
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\cmd.py", line 313, in run_command
      self.distribution.run_command(command)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
      cmd_obj.run()
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build.py", line 135, in run
      self.run_command(cmd_name)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\cmd.py", line 313, in run_command
      self.distribution.run_command(command)
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\dist.py", line 986, in run_command
      cmd_obj.run()
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 339, in run
      self.build_extensions()
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 448, in build_extensions
      self._build_extensions_serial()
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\site-packages\setuptools\_distutils\command\build_ext.py", line 473, in _build_extensions_serial
      self.build_extension(ext)
    File "C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\setup.py", line 302, in build_extension
      subprocess.check_call([sys.executable, geninterop, interop_file])
    File "c:\users\kiron\appdata\local\programs\python\python310\lib\subprocess.py", line 369, in check_call
      raise CalledProcessError(retcode, cmd)
  subprocess.CalledProcessError: Command '['c:\\users\\kiron\\appdata\\local\\programs\\python\\python310\\python.exe', 'tools\\geninterop\\geninterop.py', 'src\\runtime\\interop310.cs']' returned non-zero exit status 1.
  ----------------------------------------
  ERROR: Failed building wheel for pythonnet
  Running setup.py clean for pythonnet
Failed to build pythonnet
Installing collected packages: pythonnet
    Running setup.py install for pythonnet ... error
    ERROR: Command errored out with exit status 1:
     command: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' install --record 'C:\Users\kiron\AppData\Local\Temp\pip-record-xe4ba95q\install-record.txt' --single-version-externally-managed --compile --install-headers 'c:\users\kiron\appdata\local\programs\python\python310\Include\pythonnet'
         cwd: C:\Users\kiron\AppData\Local\Temp\pip-install-aqpb12ju\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\
    Complete output (6 lines):
    usage: setup.py [global_opts] cmd1 [cmd1_opts] [cmd2 [cmd2_opts] ...]
       or: setup.py --help [cmd1 cmd2 ...]
       or: setup.py --help-commands
       or: setup.py cmd --help

    error: option --single-version-externally-managed not recognized
    ----------------------------------------
ERROR: Command errored out with exit status 1: 'c:\users\kiron\appdata\local\programs\python\python310\python.exe' -u -c 'import io, os, sys, setuptools, tokenize; sys.argv[0] = '"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"'; __file__='"'"'C:\\Users\\kiron\\AppData\\Local\\Temp\\pip-install-aqpb12ju\\pythonnet_af0b8f5732a345fbb5e2d512446e9f59\\setup.py'"'"';f = getattr(tokenize, '"'"'open'"'"', open)(__file__) if os.path.exists(__file__) else io.StringIO('"'"'from setuptools import setup; setup()'"'"');code = f.read().replace('"'"'\r\n'"'"', '"'"'\n'"'"');f.close();exec(compile(code, __file__, '"'"'exec'"'"'))' install --record 'C:\Users\kiron\AppData\Local\Temp\pip-record-xe4ba95q\install-record.txt' --single-version-externally-managed --compile --install-headers 'c:\users\kiron\appdata\local\programs\python\python310\Include\pythonnet' Check the logs for full command output.

Now, I do see that it has something to do with my VS2019 installation, but I cannot tell what the issue is. Should I perhaps do a fresh reinstall of VS2019? And if so, what workloads and individual components should I install?

EDIT 1

I have just done a fresh reinstall of VS2019, with the following workloads, their installation detailsand the following individual components:

I'm still getting the same error in pip.

CodePudding user response：

Python.NET 2.5.2 only supports Python 3.8 or earlier. You might want to try 3.0.0 preview if you need it to run with 3.10.