I am a beginner in python and have encountered the following problem: I have a long list of strings (I took 3 now for the example):
ENSEMBL_IDs = ['ENSG00000040608',
'ENSG00000070371',
'ENSG00000070413']
which are partial matches of the data in column 0 of my DataFrame genes_df
(first 3 entries shown):
genes_list = (['ENSG00000040608.28', 'RTN4R'],
['ENSG00000070371.91', 'CLTCL1'],
['ENSG00000070413.17', 'DGCR2'])
genes_df = pd.DataFrame(genes_list)
The task I want to perform is conceptually not that difficult: I want to compare each element of ENSEMBL_IDs
to genes_df.iloc[:,0]
(which are partial matches: each element of ENSEMBL_IDs
is contained within column 0 of genes_df
, as outlined above). If the element of EMSEMBL_IDs
matches the element in genes_df.iloc[:,0]
(which it does, apart from the extra numbers after the period ".XX" ), I want to return the "corresponding" value that is stored in the first column of the genes_df
Dataframe: the actual gene name, 'RTN4R' as an example.
I want to store these in a list. So, in the end, I would be left with a list like follows:
`genenames = ['RTN4R', 'CLTCL1', 'DGCR2']`
Some info that might be helpful: all of the entries in ENSEMBL_IDs
are unique, and all of them are for sure contained in column 0 of genes_df
.
I think I am looking for something along the lines of:
`genenames = []
for i in ENSEMBL_IDs:
if i in genes_df.iloc[:,0]:
genenames.append(# corresponding value in genes_df.iloc[:,1])`
I am sorry if the question has been asked before; I kept looking and was not able to find a solution that was applicable to my problem.
Thank you for your help!
Thanks also for the edit, English is not my first language, so the improvements were insightful.
CodePudding user response:
You can get rid of the part after the dot (with str.extract
or str.replace
) before matching the values with isin
:
m = genes_df[0].str.extract('([^.] )', expand=False).isin(ENSEMBL_IDs)
# or
m = genes_df[0].str.replace('\..*$', '', regex=True).isin(ENSEMBL_IDs)
out = genes_df.loc[m, 1].tolist()
Or use a regex with str.match
:
pattern = '|'.join(ENSEMBL_IDs)
m = genes_df[0].str.match(pattern)
out = genes_df.loc[m, 1].tolist()
Output: ['RTN4R', 'CLTCL1', 'DGCR2']